They say that death and taxes are the only certainties in animation , and while we ’re still waiting for a scientific resolution to the latter of these problems , researcher from Tel Aviv University may have just made a find in the pursuance for eonian youth . In a unexampled study in the journalAging , the squad explains how they were able to arrest andreverse certain key aspects of the cellular aging processin human subjects , using a method hollo hyperbaric oxygen treatment ( HBOT ) .
The extent to which our body degenerate as we get older is believed to be dependant upon successiveness of DNA called telomeres , which are place at the ends of chromosome and protect the genetic material contained within . Yet these telomere disgrace and bowdlerize slightly each clock time a cell divides , until finally they become so worn down that they can no longer run and the whole chromosome becomes unstable .
At this spot , the cell becomes senescent , meaning it can longer continue dividing and replicating itself and is therefore essentially stagnant . As such , the shortening of telomeres and the generation of senescent cells are key tobodily aging , and are key targets for the reversal of this process .
Hyperbaric oxygen treatments demand the intake of O under eminent pressure level in club to hale more oxygen into the blood . The technique is know to upregulate the formulation of certain antioxidant genes and has been found to reduce oxidative damage . For this reason , it is commonly used to treat non - healing wound , radiation injuries , and carbon monoxide toxic condition , although the authors of the raw field of study wanted to see if it could also protect telomere from damage and increase their distance .
To find out , they administered 60 daily HBOT Roger Huntington Sessions to 35 hoi polloi , all of whom were over the long time of 64 . During treatment , participants breathed 100 pct O at a insistence of 2 right-down air for a catamenia of 90 minutes .
The researchers analyzed participant ’ lily-white profligate electric cell at the start of the test , as well as on days 30 and 60 , and again two weeks after the surcease of treatment . Results indicated that telomere lengthened by more than 20 percent in T assistant , T cytotoxic , natural killer whale and barn cell by the end of the experiment . The most dramatic increase was ensure in B cells , which displayed an median telomere lengthening of 37.63 percent two week after the net HBOT academic term .
also , treatment was associated with a significant drop in senescent bloodline cells , with the number of senescent T helper cells fall by 37.30 per centum at the two - week postdate - up pointedness .
comment on these noteworthy findings , work author Shai Efrati explicate in astatementthat “ telomere shortening is moot the ‘ Holy Grail ’ of the biology of aging . ”
“ investigator around the world are trying to build up pharmacological and environmental treatment that enable telomere extension . Our HBOT communications protocol was able to reach this , essay that the aging process can in fact be lift at the basic cellular - molecular floor , ” he enjoin .
It ’s important to note that this does n’t mean that we can now stop masses from get sometime or dying , but it ’s for sure a significant stone’s throw towards preventing and treating certain sickness that are associate with aging . And of class , if it does result in anextended human lifespanthen it will also mean more years of pay taxes .
